BAZ1A rabbit pAb

    • 货号:YT6583
    • 应用:WB
    • 种属:Human;Mouse
      • 靶点:
      • BAZ1A
      • 基因名称:
      • BAZ1A ACF1 WCRF180 HSPC317
      • 蛋白名称:
      • BAZ1A
      • Human Swiss Prot No:
      • Q9NRL2
      • Mouse Swiss Prot No:
      • O88379
      • 免疫原:
      • Synthesized peptide derived from human BAZ1A AA range: 736-786
      • 特异性:
      • This antibody detects endogenous levels of BAZ1A at Human/Mouse
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 171kD
      • 背景:
      • The BAZ1A gene encodes the accessory subunit of the ATP-dependent chromatin assembly factor (ACF), a member of the ISWI ('imitation switch') family of chromatin remodeling complexes (summarized by Racki et al., 2009 [PubMed 20033039]).[supplied by OMIM, Apr 2010],
      • 功能:
      • function:May play a role in transcriptional regulation. May be involved in the formation or maintenance of heterochromatin playing a critical role in developmental control.,miscellaneous:Stimulated by double-stranded DNA and nucleosomal DNA.,similarity:Belongs to the WAL family.,similarity:Contains 1 bromo domain.,similarity:Contains 1 DDT domain.,similarity:Contains 1 PHD-type zinc finger.,similarity:Contains 1 WAC domain.,subcellular location:May target the CHRAC complex to heterochromatin.,subunit:Together with CHRAC1, POLE3 and SMARCA5 proteins, it forms the ISWI chromatin-remodeling complex, CHRAC.,tissue specificity:Highly expressed in testis and at low or undetectable levels in other tissues analyzed.,
      • 细胞定位:
      • Nucleus. May target the CHRAC complex to heterochromatin.
      • 组织表达:
      • Highly expressed in testis and at low or undetectable levels in other tissues analyzed.
      • 产品图片
      • Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night