• 靶点：
• PYDC1

• 简介：
• >>NOD-like receptor signaling pathway

• 基因名称：
• PYDC1 ASC2 ASCI POP1 PYC1

• 蛋白名称：
• PYDC1

• Human Gene Id：
• 260434

• Human Swiss Prot No：
• Q8WXC3

• 免疫原：
• Synthesized peptide derived from human PYDC1 AA range: 25-75

• 特异性：
• This antibody detects endogenous levels of PYDC1 at Human

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1：50-200. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 10kD

• 功能：
• function:Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.,PTM:Phosphorylated.,similarity:Contains 1 DAPIN domain.,subunit:Interacts with PYCARD/ASC.,tissue specificity:Predominantly expressed in monocytes, macrophages and granulocytes.,

• 细胞定位：
• Cytoplasm . Recruited to specks formed by PYCARD within the cytoplasm. .

• 组织表达：
• Predominantly expressed in monocytes, macrophages and granulocytes.

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