• 靶点：
• GCM1

• 简介：
• >>Parathyroid hormone synthesis, secretion and action

• 基因名称：
• GCM1 GCMA

• 蛋白名称：
• GCM1

• Human Gene Id：
• 8521

• Human Swiss Prot No：
• Q9NP62

• Mouse Gene Id：
• 14531

• Mouse Swiss Prot No：
• P70348

• Rat Gene Id：
• 29394

• Rat Swiss Prot No：
• Q9Z288

• 免疫原：
• Synthesized peptide derived from human GCM1 AA range: 298-348

• 特异性：
• This antibody detects endogenous levels of GCM1 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 48kD

• 背景：
• This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008],

• 功能：
• function:Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer.,similarity:Contains 1 GCM DNA-binding domain.,tissue specificity:Placenta specific.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Highly expressed in the placenta (PubMed:10542267). Expressed in trophoblast cells of the villi (PubMed:27917469).

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