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RIPK4 rabbit pAb

货号：YT6530
应用：WB
种属：Human;Mouse

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靶点：
RIPK4

基因名称：
RIPK4 ANKRD3 DIK

蛋白名称：
RIPK4

Human Swiss Prot No：
P57078

Mouse Gene Id：
72388

Mouse Swiss Prot No：
Q9ERK0

免疫原：
Synthesized peptide derived from human RIPK4 AA range: 280-330

特异性：
This antibody detects endogenous levels of RIPK4 at Human/Mouse

组成：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

来源：
Polyclonal, Rabbit,IgG

稀释：
WB 1：500-2000

纯化工艺：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度：
1 mg/ml

储存：
-15°C to -25°C/1 year(Do not lower than -25°C)

分子量：
92kD

背景：
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008],

功能：
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Plays a role in NF-kappa B activation.,PTM:May be phosphorylated by MAP3K2 and MAP3K3.,PTM:Proteolytically cleaved by during Fas-induced apoptosis. Cleavage at Asp-388 and Asp-426.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 10 ANK repeats.,subunit:Interacts with PRKCB (By similarity). Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.,

细胞定位：
Cytoplasm. Membrane ; Peripheral membrane protein .

组织表达：
Expressed in hair follicles and skin.

Downregulation of RIPK4 Expression Inhibits Epithelial-Mesenchymal Transition in Ovarian Cancer through IL-6. Journal of Immunology Research J Immunol Res. 2021;2021:8875450 WB Human 1 : 1000 SKOV3 cell
货号：YT6530