• 靶点：
• EXTL2

• 简介：
• >>Glycosaminoglycan biosynthesis - heparan sulfate / heparin;>>Metabolic pathways

• 基因名称：
• EXTL2 EXTR2

• 蛋白名称：
• EXTL2

• Human Gene Id：
• 2135

• Human Swiss Prot No：
• Q9UBQ6

• Mouse Gene Id：
• 58193

• Mouse Swiss Prot No：
• Q9ES89

• 免疫原：
• Synthesized peptide derived from human EXTL2 AA range: 141-191

• 特异性：
• This antibody detects endogenous levels of EXTL2 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 36kD

• 功能：
• catalytic activity:UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.,function:Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.,online information:Exostosin-like 2,online information:GlycoGene database,pathway:Glycan metabolism; heparan sulfate biosynthesis.,PTM:The soluble form derives from the membrane form by proteolytic processing.,similarity:Belongs to the glycosyltransferase 47 family.,subcellular location:A soluble form is found in the serum.,tissue specifi

• 细胞定位：
• Endoplasmic reticulum membrane ; Single-pass type II membrane protein .; [Processed exostosin-like 2]: Secreted. A soluble form is found in the serum.

• 组织表达：
• Ubiquitous.

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