- 靶点:
- ACADL
- 简介:
- >>Fatty acid degradation;>>Metabolic pathways;>>Fatty acid metabolism;>>PPAR signaling pathway
- 基因名称:
- ACADL
- 蛋白名称:
- ACADL
- Human Gene Id:
- 33
- Human Swiss Prot No:
- P28330
- Mouse Gene Id:
- 11363
- Mouse Swiss Prot No:
- P51174
- Rat Gene Id:
- 25287
- Rat Swiss Prot No:
- P15650
- 免疫原:
- Synthesized peptide derived from human ACADL AA range: 258-308
- 特异性:
- This antibody detects endogenous levels of ACADL at Human/Mouse/Rat
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 分子量:
- 47kD
- 背景:
- The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008],
- 功能:
- catalytic activity:Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.,cofactor:FAD.,disease:Impaired ACADL activity results in non-ketotic hypoglycemia, hypotonia, muscle weakness and episodes of cardiorespiratory arrest associated with fasting [MIM:201460].,miscellaneous:A number of straight-chain acyl-CoA dehydrogenases of different substrate specificities are present in mammalian tissues.,pathway:Lipid metabolism; mitochondrial fatty acid beta-oxidation.,similarity:Belongs to the acyl-CoA dehydrogenase family.,subunit:Homotetramer.,
- 细胞定位:
- Mitochondrion matrix .
Bifidobacterium animalis subsp. lactis A6 Enhances Fatty Acid β-Oxidation of Adipose Tissue to Ameliorate the Development of Obesity in Mice Nutrients. 2022 Jan;14(3):598. WB Mouse epididymal adipose tissues
货号:YT6498
Identification and Verification of Hub Mitochondrial Dysfunction Genes in Osteoarthritis Based on Bioinformatics Analysis Journal of Immunology Research Hui Niu WB Human 1:1000 Chondrocytes
货号:YT6498
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- Antibody-FAQs
- 产品图片
- Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night