K1731 rabbit pAb

    • 货号:YT6425
    • 应用:IHC;IF
    • 种属:Human;Mouse;Rat
      • 靶点:
      • K1731
      • 基因名称:
      • KIAA1731
      • 蛋白名称:
      • K1731
      • Human Swiss Prot No:
      • Q9C0D2
      • Mouse Swiss Prot No:
      • Q8BQ48
      • 免疫原:
      • Synthesized peptide derived from human K1731 AA range: 208-258
      • 特异性:
      • This antibody detects endogenous levels of K1731 at Human/Mouse/Rat
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:50-200. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 286kD
      • 功能:
      • sequence caution:Translation N-terminally shortened.,similarity:Contains 7 LRR (leucine-rich) repeats.,
      • 细胞定位:
      • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton . Associates with both of the converted centrioles during G1 but becomes more enriched at the newly formed daughter (or unconverted) centrioles during S, G2, and early M phases (PubMed:25131205, PubMed:32060285). In early S phase, localized at the procentriolar microtubule wall and enriched at the proximal ends of the centrioles in CENPJ- and CEP135-dependent manner (PubMed:27185865). Colocalizes with SASS6 and CEP250 proteins (PubMed:25131205). Colocalizes with CEP135 and CEP192 at the centrosomes (PubMed:27185865). Associates with interphase microtubules and mitotic spindles (PubMed:
      • 产品图片
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).