MICA1 rabbit pAb

    • 货号:YT6400
    • 应用:WB;IHC
    • 种属:Human;Mouse;Rat
      • 靶点:
      • MICA1
      • 基因名称:
      • MICAL1 MICAL NICAL
      • 蛋白名称:
      • MICA1
      • Human Swiss Prot No:
      • Q8TDZ2
      • Mouse Swiss Prot No:
      • Q8VDP3
      • 免疫原:
      • Synthesized peptide derived from human MICA1 AA range: 155-205
      • 特异性:
      • This antibody detects endogenous levels of MICA1 at Human/Mouse/Rat
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 117kD
      • 背景:
      • This gene encodes an enzyme that oxidizes methionine residues on actin, thereby promoting depolymerization of actin filaments. This protein interacts with and regulates signalling by NEDD9/CAS-L (neural precursor cell expressed, developmentally down-regulated 9). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],
      • 功能:
      • cofactor:FAD .,domain:The C-terminal coiled coil part contains the plexin-interacting region.,function:May be a cytoskeletal regulator that connects NEDD9 to intermediate filaments.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 LIM zinc-binding domain.,subunit:Associates with the SH3 domain of NEDD9. Interacts with VIM and PLXNA3. Interacts with RAB1B.,tissue specificity:Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.,
      • 细胞定位:
      • Cytoplasm. Cytoplasm, cytoskeleton. Midbody . Accumulates transiently at the abscission site before abscission occurs. .
      • 组织表达:
      • Expressed in the thymus, lung, spleen, kidney, testis and hematopoietic cells.
      • 产品图片
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).