Flotillin-1 Polyclonal Antibody
- 货号：YT6292
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Insulin signaling pathway
- 免疫原：
- Synthesized peptide derived from human Flotillin-1
- 特异性：
- This antibody detects endogenous levels of human Flotillin-1
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500-2000, ELISA(peptide)1:5000-20000
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景：
- This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
- 功能：
- function:May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.,similarity:Belongs to the band 7/mec-2 family. Flotillin subfamily.,subcellular location:Membrane-associated protein of caveolae. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2.,
- 细胞定位：
- Cell membrane; Peripheral membrane protein . Endosome . Membrane, caveola ; Peripheral membrane protein . Melanosome . Membrane raft . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Membrane-associated protein of caveola (By similarity). .
- 组织表达：
- Adipose tissue,Adrenal gland,Lung,Peripheral blood leukocyte,Umbilical cord blood,
- Western blot analysis of various lysates, primary antibody was diluted at 1:1000, 4° over night, secondary antibody(cat: RS23920)was diluted at 1:10000, 37° 1hour.
