Secretogranin-1 Polyclonal Antibody
- 货号：YT6192
- 应用：IHC;IF;WB
- 种属：Human;Mouse;Rat
- 免疫原：
- Synthesized peptide derived from human Secretogranin-1
- 特异性：
- This antibody detects endogenous levels of human Secretogranin-1
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:50-200, WB 1:500-2000. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Secretogranin-1 (Chromogranin-B;CgB;Secretogranin I;SgI) [Cleaved into: GAWK peptide;CCB peptide]
- 背景：
- This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009],
- 功能：
- function:Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,PTM:Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.,
- 细胞定位：
- Secreted. Neuroendocrine and endocrine secretory granules.
- 组织表达：
- Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
