Tubulin γ Polyclonal Antibody
- 货号：YT6011
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Human papillomavirus infection
- 蛋白名称：
- Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1)
- 免疫原：
- Synthetic peptide from human protein at AA range: 380-440
- 特异性：
- The antibody detects endogenous Tubulin γ
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- Tubulin gamma-1 chain (Gamma-1-tubulin;Gamma-tubulin complex component 1;GCP-1)
- 背景：
- This gene encodes a member of the tubulin superfamily. The encoded protein localizes to the centrosome where it binds to microtubules as part of a complex referred to as the gamma-tubulin ring complex. The protein mediates microtubule nucleation and is required for microtubule formation and progression of the cell cycle. A pseudogene of this gene is found on chromosome 7. [provided by RefSeq, Jan 2009],
- 功能：
- function:Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.,mass spectrometry: PubMed:11840567,similarity:Belongs to the tubulin family.,subunit:Interacts with GCP2 and GCP3. Interacts with B9D2.,
- 细胞定位：
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Localizes to mitotic spindle microtubules. .
- 组织表达：
- Mammary cancer,Skin,
- Immunohistochemical analysis of paraffin-embedded Human-testis, antibody was diluted at 1:100
