ATG10 Polyclonal Antibody
- 货号:YT6005
- 应用:IHC;IF;ELISA
- 种属:Human;Mouse
- 简介:
- >>Autophagy - other;>>Autophagy - animal
- 基因名称:
- ATG10 APG10L PP12616
- 蛋白名称:
- Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-) (Autophagy-related protein 10) (APG10-like)
- 免疫原:
- Synthetic peptide from human protein at AA range: 1-50
- 特异性:
- The antibody detects endogenous ATG10
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-;Autophagy-related protein 10;APG10-like)
- 背景:
- Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008],
- 功能:
- function:Plays a role in autophagy (By similarity). ATG12-conjugating enzyme (E2-like enzyme), likely serves as an ATG5-recognition molecule.,similarity:Belongs to the ATG10 family.,subunit:Interacts with MAP1LC3A. By interacting with MAP1LC3A, it plays a role in the conjugation of ATG12 to ATG5. Also able to directly interact either with ATG5 or ATG7.,
- 组织表达:
- Placenta,Testis,Thymus,Uterus,
- Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200
- Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:200