• 靶点：
• AVP Receptor V3

• 简介：
• >>Calcium signaling pathway;>>Phospholipase D signaling pathway;>>Neuroactive ligand-receptor interaction;>>Vascular smooth muscle contraction

• 基因名称：
• AVPR1B AVPR3 VPR3

• 蛋白名称：
• Vasopressin V1b receptor (V1bR) (AVPR V1b) (AVPR V3) (Antidiuretic hormone receptor 1b) (Vasopressin V3 receptor)

• Human Gene Id：
• 553

• Human Swiss Prot No：
• P47901

• Mouse Gene Id：
• 26361

• Mouse Swiss Prot No：
• Q9WU02

• Rat Swiss Prot No：
• P48974

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320

• 特异性：
• The antibody detects endogenous AVP Receptor V3

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Vasopressin V1b receptor (V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor)

• 背景：
• The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],

• 功能：
• function:Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein .

• 组织表达：
• Lung carcinoma,Pituitary,

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