PACAP Polyclonal Antibody
- 货号:YT5998
- 应用:IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 蛋白名称:
- Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein) (pERp1) (Proapoptotic caspase adapter protein)
- 免疫原:
- Synthetic peptide from human protein at AA range: 1-50
- 特异性:
- The antibody detects endogenous PACAP
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein;pERp1;Proapoptotic caspase adapter protein)
- 背景:
- function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
- 功能:
- function:May be involved in regulation of apoptosis.,induction:Down-regulated in primary B-cells early after ligand-stimulated activation.,subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus.,subunit:Isoform 2 interacts with CASP2 and CASP9.,tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.,
- 细胞定位:
- [Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957).
- 组织表达:
- Widely expressed with highest levels in adult brain, small intestine and lymphoid tissues such as thymus and spleen. Expression is frequently lower in intestinal-type gastric cancer. In obese patients, more abundant in omental than in subcutaneous fat.
![](/uploadfiles/PIC/yt5998ihc-human-testis.jpg)
- Immunohistochemical analysis of paraffin-embedded human-testis, antibody was diluted at 1:200