Flt3-L Polyclonal Antibody
- 货号:YT5516
- 应用:WB;ELISA
- 种属:Human;Rat;Mouse;
- 简介:
- >>MAPK signaling pathway;>>Ras signaling pathway;>>PI3K-Akt signaling pathway;>>Hematopoietic cell lineage;>>Pathways in cancer
- 蛋白名称:
- Fms-related tyrosine kinase 3 ligand
- 免疫原:
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human FLT3LG. AA range:171-220
- 特异性:
- Flt3-L Polyclonal Antibody detects endogenous levels of Flt3-L protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- FLT3LG;Fms-related tyrosine kinase 3 ligand;Flt3 ligand;Flt3L;SL cytokine
- 背景:
- Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011],
- 功能:
- function:Stimulates the proliferation of early hematopoietic cells. Synergizes well with a number of other colony stimulating factors and interleukins.,subunit:Homodimer (isoform 2).,
- 细胞定位:
- [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.
- Western Blot analysis of HeLa cells using Flt3-L Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000