• 靶点：
• CD48

• 简介：
• >>Natural killer cell mediated cytotoxicity

• 基因名称：
• CD48

• 蛋白名称：
• CD48 antigen

• Human Gene Id：
• 962

• Human Swiss Prot No：
• P09326

• Mouse Swiss Prot No：
• P18181

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human CD48. AA range:41-90

• 特异性：
• CD48 Polyclonal Antibody detects endogenous levels of CD48 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CD48;BCM1;BLAST1;CD48 antigen;B-lymphocyte activation marker BLAST-1;BCM1 surface antigen;Leukocyte antigen MEM-102;TCT.1;CD48

• 实测条带：
• 40kD

• 背景：
• This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],

• 功能：
• function:Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,

• 细胞定位：
• Cell membrane ; Lipid-anchor, GPI-anchor . Secreted .

• 组织表达：
• Widely expressed on all hematopoietic cells.

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