• 靶点：
• ET-1

• 简介：
• >>cAMP signaling pathway;>>HIF-1 signaling pathway;>>Neuroactive ligand-receptor interaction;>>Vascular smooth muscle contraction;>>TNF signaling pathway;>>Melanogenesis;>>Renin secretion;>>Relaxin signaling pathway;>>AGE-RAGE signaling pathway in diabetic complications;>>Pathways in cancer;>>Hypertrophic cardiomyopathy;>>Fluid shear stress and atherosclerosis

• 基因名称：
• EDN1

• 蛋白名称：
• Endothelin-1

• Human Gene Id：
• 1906

• Human Swiss Prot No：
• P05305

• Mouse Swiss Prot No：
• P22387

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180

• 特异性：
• ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• EDN1;Endothelin-1;Preproendothelin-1;PPET1

• 实测条带：
• 25kD

• 背景：
• This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

• 功能：
• function:Endothelins are endothelium-derived vasoconstrictor peptides.,online information:Endothelin entry,similarity:Belongs to the endothelin/sarafotoxin family.,tissue specificity:Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.,

• 细胞定位：
• Secreted.

• 组织表达：
• Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs