• 靶点：
• USP30

• 简介：
• >>Mitophagy - animal

• 基因名称：
• USP30

• 蛋白名称：
• Ubiquitin carboxyl-terminal hydrolase 30

• Human Gene Id：
• 84749

• Human Swiss Prot No：
• Q70CQ3

• Mouse Gene Id：
• 100756

• Mouse Swiss Prot No：
• Q3UN04

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human USP30. AA range:31-80

• 特异性：
• USP30 Polyclonal Antibody detects endogenous levels of USP30 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• USP30;Ubiquitin carboxyl-terminal hydrolase 30;Deubiquitinating enzyme 30;Ubiquitin thioesterase 30;Ubiquitin-specific-processing protease 30;Ub-specific protease 30

• 实测条带：
• 60kd,unspecial bands( 65kd,105kd,130kd)in Hela and HCT116 cell.

• 背景：
• USP30, a member of the ubiquitin-specific protease family (see USP1, MIM 603478), is a novel mitochondrial deubiquitinating (DUB) enzyme (Nakamura and Hirose, 2008 [PubMed 18287522]).[supplied by OMIM, Dec 2008],

• 功能：
• catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May participate in the maintenance of mitochondrial morphology.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in skeletal muscle, pancreas, liver and kidney.,

• 细胞定位：
• Mitochondrion outer membrane .

• 组织表达：
• Expressed in skeletal muscle, pancreas, liver and kidney.

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