USP15 Polyclonal Antibody
- 货号：YT4830
- 应用：WB;ELISA
- 种属：Human;Mouse;Rat
- 蛋白名称：
- Ubiquitin carboxyl-terminal hydrolase 15
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human USP15. AA range:81-130
- 特异性：
- USP15 Polyclonal Antibody detects endogenous levels of USP15 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- USP15;KIAA0529;Ubiquitin carboxyl-terminal hydrolase 15;Deubiquitinating enzyme 15;Ubiquitin thioesterase 15;Ubiquitin-specific-processing protease 15;Unph-2;Unph4
- 背景：
- This gene encodes a member of the ubiquitin specific protease (USP) family of deubiquitinating enzymes. USP enzymes play critical roles in ubiquitin-dependent processes through polyubiquitin chain disassembly and hydrolysis of ubiquitin-substrate bonds. The encoded protein associates with the COP9 signalosome, and also plays a role in transforming growth factor beta signalling through deubiquitination of receptor-activated SMAD transcription factors. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 2. [provided by RefSeq, Nov 2011],
- 功能：
- catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 DUSP domain.,tissue specificity:Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.,
- 细胞定位：
- Cytoplasm . Nucleus . Mitochondrion .
- 组织表达：
- Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.
- Western blot analysis of the lysates from HeLa cells using USP15 antibody.
