UBE2G1 Polyclonal Antibody
- 货号：YT4799
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Ubiquitin mediated proteolysis;>>Protein processing in endoplasmic reticulum;>>Parkinson disease;>>Pathways of neurodegeneration - multiple diseases
- 蛋白名称：
- Ubiquitin-conjugating enzyme E2 G1
- 免疫原：
- Synthesized peptide derived from the Internal region of human UBE2G1.
- 特异性：
- UBE2G1 Polyclonal Antibody detects endogenous levels of UBE2G1 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- UBE2G1;UBE2G;Ubiquitin-conjugating enzyme E2 G1;E217K;UBC7;Ubiquitin carrier protein G1;Ubiquitin-protein ligase G1
- 背景：
- The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008],
- 功能：
- catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins. May be involved in degradation of muscle-specific proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,tissue specificity:Widely expressed, mainly in skeletal muscle.,
- 细胞定位：
- cytoplasm,extracellular exosome,
- 组织表达：
- Widely expressed, mainly in skeletal muscle.
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
