TUSC2 Polyclonal Antibody
- 货号:YT4783
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Tumor suppressor candidate 2
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human TUSC2. AA range:41-90
- 特异性:
- TUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- TUSC2;C3orf11;FUS1;LGCC;PDAP2;Tumor suppressor candidate 2;Fusion 1 protein;Fus-1 protein;PDGFA-associated protein 2
- 背景:
- This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],
- 功能:
- function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,
- 组织表达:
- Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
- Western Blot analysis of 293T cells using TUSC2 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Human heart. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
- Western blot analysis of lysates from HeLa cells, using TUSC2 Antibody. The lane on the right is blocked with the synthesized peptide.