TReP-132 Polyclonal Antibody
- 货号:YT4732
- 应用:IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Transcriptional-regulating factor 1
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human TREF1. AA range:1071-1120
- 特异性:
- TReP-132 Polyclonal Antibody detects endogenous levels of TReP-132 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- TRERF1;BCAR2;RAPA;TREP132;Transcriptional-regulating factor 1;Breast cancer anti-estrogen resistance 2;Transcriptional-regulating protein 132;Zinc finger protein rapa;Zinc finger transcription factor TReP-132
- 背景:
- This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],
- 功能:
- function:Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.,similarity:Contains 1 ELM2 domain.,similarity:Contains 1 SANT domain.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with CREBBP and EP300.,tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.,
- 组织表达:
- Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic Hep-G2 and HEK293 cells.
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TREF1 Antibody. The picture on the right is blocked with the synthesized peptide.