TP53INP2 Polyclonal Antibody

    • 货号:YT4706
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • TP53INP2
      • 简介:
      • >>Autophagy - animal
      • 基因名称:
      • TP53INP2
      • 蛋白名称:
      • Tumor protein p53-inducible nuclear protein 2
      • Human Swiss Prot No:
      • Q8IXH6
      • Mouse Swiss Prot No:
      • Q8CFU8
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human TP53INP2. AA range:1-50
      • 特异性:
      • TP53INP2 Polyclonal Antibody detects endogenous levels of TP53INP2 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • TP53INP2;C20orf110;DOR;PINH;Tumor protein p53-inducible nuclear protein 2;Diabetes and obesity-regulated gene;p53-inducible protein U;PIG-U
      • 分子量:
      • 24kD
      • 实测条带:
      • 17kD
      • 背景:
      • tumor protein p53 inducible nuclear protein 2(TP53INP2) Homo sapiens The protein encoded by this gene promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1/RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes. [provided by RefSeq, Jul 2016],
      • 细胞定位:
      • Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome. Shuttles between the nucleus and the cytoplasm, depending on cellular stress conditions, and re-localizes to autophagosomes on autophagy activation.
      • 组织表达:
      • Eye,Heart,
      • 产品图片
      • Immunofluorescence analysis of MCF7 cells, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TP53INP2 Antibody. The picture on the right is blocked with the synthesized peptide.