• 靶点：
• TDE1

• 简介：
• >>Viral life cycle - HIV-1

• 基因名称：
• SERINC3

• 蛋白名称：
• Serine incorporator 3

• Human Gene Id：
• 10955

• Human Swiss Prot No：
• Q13530

• Mouse Gene Id：
• 26943

• Mouse Swiss Prot No：
• Q9QZI9

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human SERC3. AA range:361-410

• 特异性：
• TDE1 Polyclonal Antibody detects endogenous levels of TDE1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SERINC3;DIFF33;TDE1;SBBI99;Serine incorporator 3;Tumor differentially expressed protein 1

• 实测条带：
• 52kD

• 背景：
• function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,

• 功能：
• function:May be involved in cellular transformation.,PTM:N-glycosylated.,similarity:Belongs to the TDE1 family.,tissue specificity:Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .; Cytoplasm, perinuclear region . (Microbial infection) Upon HIV-1 infection, it is redirected to perinuclear region following interaction with HIV-1 Nef, excluding it from virions particles, thereby preventing subsequent antiviral defense activity (Probable). .

• 组织表达：
• Ubiquitous. Expression levels were increased fourfold to tenfold in lung tumor tissues compared with normal pulmonary tissues.

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