TCP-1 ζ Polyclonal Antibody
- 货号：YT4585
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Mouse;Rat
- 蛋白名称：
- T-complex protein 1 subunit zeta
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human CCT6A. AA range:171-220
- 特异性：
- TCP-1 ζ Polyclonal Antibody detects endogenous levels of TCP-1 ζ protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- CCT6A;CCT6;CCTZ;T-complex protein 1 subunit zeta;TCP-1-zeta;Acute morphine dependence-related protein 2;CCT-zeta-1;HTR3;Tcp20
- 背景：
- The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010],
- 功能：
- caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.,similarity:Belongs to the TCP-1 chaperonin family.,subunit:Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.,
- 组织表达：
- B-cell,Brain,Cajal-Retzius cell,Platelet,
- Western Blot analysis of various cells using TCP-1 ζ Polyclonal Antibody diluted at 1:500
- Western blot analysis of CCT6A Antibody. The lane on the right is blocked with the CCT6A peptide.
- Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CCT6A Antibody. The picture on the right is blocked with the synthesized peptide.
