SR-5A Polyclonal Antibody
- 货号：YT4405
- 应用：WB;IF;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction;>>Serotonergic synapse
- 蛋白名称：
- 5-hydroxytryptamine receptor 5A
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64
- 特异性：
- SR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- HTR5A;5-hydroxytryptamine receptor 5A;5-HT-5;5-HT-5A;5-HT5A;Serotonin receptor 5A
- 背景：
- The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],
- 功能：
- function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- 细胞定位：
- Cell membrane; Multi-pass membrane protein.
- Immunofluorescence analysis of LOVO cells, using HTR5A Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from Jurkat cells, using HTR5A Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HepG2 cells using HTR5A antibody.
