• 靶点：
• SPZ1

• 基因名称：
• SPZ1

• 蛋白名称：
• Spermatogenic leucine zipper protein 1

• Human Gene Id：
• 84654

• Human Swiss Prot No：
• Q9BXG8

• Mouse Swiss Prot No：
• Q99MY0

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human SPZ1. AA range:111-160

• 特异性：
• SPZ1 Polyclonal Antibody detects endogenous levels of SPZ1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SPZ1;TSP1;Spermatogenic leucine zipper protein 1;Testis-specific protein 1;Testis-specific protein NYD-TSP1

• 实测条带：
• 133kD

• 背景：
• This gene encodes a bHLH-zip transcription factor which functions in the mitogen-activate protein kinase (MAPK) signaling pathway. Because of its role in the upregulation of cell proliferation and tumorigenesis, this gene may serve as a target for Ras-induced tumor treatments. [provided by RefSeq, Oct 2011],

• 功能：
• function:Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.,PTM:Phosphorylated by ERK1 and ERK2.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with PPP1CC isoform gamma-2.,tissue specificity:Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.,

• 细胞定位：
• Cytoplasm . Nucleus .

• 组织表达：
• Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.

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