- 靶点:
- SMIT
- 基因名称:
- SLC5A3
- 蛋白名称:
- Sodium/myo-inositol cotransporter
- Human Gene Id:
- 6526
- Human Swiss Prot No:
- P53794
- Mouse Gene Id:
- 53881
- Mouse Swiss Prot No:
- Q9JKZ2
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human SLC5A3. AA range:221-270
- 特异性:
- SMIT Polyclonal Antibody detects endogenous levels of SMIT protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- SLC5A3;Sodium/myo-inositol cotransporter;Na(+)/myo-inositol cotransporter;Sodium/myo-inositol transporter 1;SMIT1;Solute carrier family 5 member 3
- 实测条带:
- 80kD
- 背景:
- function:Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.,
- 功能:
- function:Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.,
- 细胞定位:
- Membrane; Multi-pass membrane protein.
- 组织表达:
- Placenta,
Corosolic acid inhibits cancer progression by decreasing the level of CDK19-mediated O-GlcNAcylation in liver cancer cells. Cell Death & Disease Cell Death Dis. 2021 Sep;12(10):1-11 IHC Mouse 1:200 Bel-7404 cell-Xenograft
货号:YT4344
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of various cells using SMIT Polyclonal Antibody diluted at 1:500
- Western Blot analysis of HuvEc cells using SMIT Polyclonal Antibody diluted at 1:500
- Western blot analysis of lysates from HUVEC cells, using SLC5A3 Antibody. The lane on the right is blocked with the synthesized peptide.
- Immunohistochemical analysis of paraffin-embedded human Colon cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).