• 靶点：
• Septin 3

• 简介：
• >>Bacterial invasion of epithelial cells;>>Shigellosis

• 基因名称：
• SEPT3

• 蛋白名称：
• Neuronal-specific septin-3

• Human Gene Id：
• 55964

• Human Swiss Prot No：
• Q9UH03

• Mouse Gene Id：
• 24050

• Mouse Swiss Prot No：
• Q9Z1S5

• Rat Gene Id：
• 56003

• Rat Swiss Prot No：
• Q9WU34

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human SEPT3. AA range:136-185

• 特异性：
• Septin 3 Polyclonal Antibody detects endogenous levels of Septin 3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SEPT3;SEP3;Neuronal-specific septin-3

• 实测条带：
• 41kD

• 背景：
• septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

• 功能：
• function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific.,

• 细胞定位：
• Cytoplasm. Cytoplasm, cytoskeleton . Cell junction, synapse .

• 组织表达：
• Brain-specific.

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