Septin 1 Polyclonal Antibody

    • 货号:YT4245
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Mouse;Rat
      • 靶点:
      • Septin 1
      • 简介:
      • >>Bacterial invasion of epithelial cells
      • 基因名称:
      • SEPT1
      • 蛋白名称:
      • Septin-1
      • Human Gene Id:
      • 1731
      • Human Swiss Prot No:
      • Q8WYJ6
      • Mouse Swiss Prot No:
      • P42209
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human SEPT1. AA range:181-230
      • 特异性:
      • Septin 1 Polyclonal Antibody detects endogenous levels of Septin 1 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • SEPT1;DIFF6;PNUTL3;Septin-1;LARP;Peanut-like protein 3;Serologically defined breast cancer antigen NY-BR-24
      • 实测条带:
      • 41kD
      • 背景:
      • septin 1(SEPT1) Homo sapiens This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012],
      • 功能:
      • function:Involved in cytokinesis .,similarity:Belongs to the septin family.,subunit:May assemble into a multicomponent structure.,
      • 细胞定位:
      • Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
      • 组织表达:
      • Expressed at high levels in lymphoid and hematopoietic tissues.
      • 产品图片
      • Western Blot analysis of various cells using Septin 1 Polyclonal Antibody
      • Western blot analysis of lysates from Jurkat cells, using SEPT1 Antibody. The lane on the right is blocked with the synthesized peptide.
      • Immunohistochemical analysis of paraffin-embedded human spleen tissue. 1,primary Antibody was diluted at 1:200(4° overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200