SENP7 Polyclonal Antibody
- 货号：YT4241
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Mouse
- 蛋白名称：
- Sentrin-specific protease 7
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human SENP7. AA range:991-1040
- 特异性：
- SENP7 Polyclonal Antibody detects endogenous levels of SENP7 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SENP7;KIAA1707;SSP2;SUSP2;Sentrin-specific protease 7;SUMO-1-specific protease 2;Sentrin/SUMO-specific protease SENP7
- 背景：
- The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009],
- 功能：
- alternative products:Experimental confirmation may be lacking for some isoforms,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.,similarity:Belongs to the peptidase C48 family.,
- 组织表达：
- Brain,Epithelium,Fetal kidney,Placenta,
- Western Blot analysis of various cells using SENP7 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using SENP7 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from HUVEC cells, using SENP7 Antibody. The lane on the right is blocked with the synthesized peptide.
