• 靶点：
• SENP5

• 基因名称：
• SENP5

• 蛋白名称：
• Sentrin-specific protease 5

• Human Gene Id：
• 205564

• Human Swiss Prot No：
• Q96HI0

• Mouse Gene Id：
• 320213

• Mouse Swiss Prot No：
• Q6NXL6

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700

• 特异性：
• SENP5 Polyclonal Antibody detects endogenous levels of SENP5 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SENP5;FKSG45;Sentrin-specific protease 5;Sentrin/SUMO-specific protease SENP5

• 实测条带：
• 86kD

• 背景：
• The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],

• 功能：
• function:Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.,similarity:Belongs to the peptidase C48 family.,

• 细胞定位：
• Nucleus, nucleolus .

• 组织表达：
• Placenta,Testis,

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