S-100A3 Polyclonal Antibody
- 货号:YT4200
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human S100A3. AA range:26-75
- 特异性:
- S-100A3 Polyclonal Antibody detects endogenous levels of S-100A3 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- S100A3;S100E;Protein S100-A3;Protein S-100E;S100 calcium-binding protein A3
- 背景:
- S100 calcium binding protein A3(S100A3) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008],
- 功能:
- function:Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Skin specific.,
- 组织表达:
- Skin specific, specifically expressed at the inner endocuticle of hair fibers.
![](/uploadfiles/PIC/yt4200_pic738218522.jpg)
- Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using S100A3 Antibody. The picture on the right is blocked with the synthesized peptide.