ROR2 Polyclonal Antibody

  • 货号：YT4165
  • 应用：WB;ELISA
  • 种属：Human;Mouse;Rat
    • 靶点：
    • ROR2
    • 简介：
    • >>Wnt signaling pathway
    • 基因名称：
    • ROR2
    • 蛋白名称：
    • Tyrosine-protein kinase transmembrane receptor ROR2
    • Human Gene Id：
    • 4920
    • Human Swiss Prot No：
    • Q01974
    • Mouse Swiss Prot No：
    • Q9Z138
    • 免疫原：
    • Synthesized peptide derived from ROR2 . at AA range: 450-530
    • 特异性：
    • ROR2 Polyclonal Antibody detects endogenous levels of ROR2 protein.
    • 组成：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源：
    • Polyclonal, Rabbit,IgG
    • 稀释：
    • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
    • 纯化工艺：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度：
    • 1 mg/ml
    • 储存：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称：
    • ROR2;NTRKR2;Tyrosine-protein kinase transmembrane receptor ROR2;Neurotrophic tyrosine kinase; receptor-related 2
    • 实测条带：
    • 110kD
    • 背景：
    • The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. [provided by RefSeq, Jul 2008],
    • 功能：
    • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,developmental stage:Expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues.,disease:Defects in ROR2 are a cause of brachydactyly type B1 (BDB1) [MIM:113000]. BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed.,disease:Defects in ROR2 are a cause of recessive Robinow syndrome (RRS) [MIM:268310]. RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a
    • 细胞定位：
    • Cell membrane ; Single-pass type I membrane protein .
    • 组织表达：
    • Brain,

    Indirect co‑culture of vascular smooth muscle cells with bone marrow mesenchymal stem cells inhibits vascular calcification and downregulates the Wnt signaling pathways. Molecular Medicine Reports Mol Med Rep. 2016 Jun;13(6):5141-5148 WB Rat 1:500 MSCs
    货号：YT4165

    相关报价

    • 货号：
    • YT4165
    • 规格：
    • 40μL / 100μL / 200μL
    • 价格：
    • ¥960 / 2300 / 3780
    • 货期：
    • 预计发货时间为
      2024-11-24
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