RN-tre Polyclonal Antibody

    • 货号:YT4158
    • 应用:IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • RN-tre
      • 基因名称:
      • USP6NL
      • 蛋白名称:
      • USP6 N-terminal-like protein
      • Human Gene Id:
      • 9712
      • Human Swiss Prot No:
      • Q92738
      • Mouse Swiss Prot No:
      • Q80XC3
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human USP6NL. AA range:451-500
      • 特异性:
      • RN-tre Polyclonal Antibody detects endogenous levels of RN-tre protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • USP6NL;KIAA0019;USP6 N-terminal-like protein;Related to the N-terminus of tre;RN-tre
      • 分子量:
      • 94kD
      • 背景:
      • function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed.,
      • 功能:
      • function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 Rab-GAP TBC domain.,subunit:Interacts with EPS8.,tissue specificity:Widely expressed.,
      • 细胞定位:
      • Golgi apparatus. Cytoplasmic vesicle.
      • 组织表达:
      • Widely expressed.
      • 产品图片
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using USP6NL Antibody. The picture on the right is blocked with the synthesized peptide.