- 靶点:
- PREP-2
- 基因名称:
- PKNOX2
- 蛋白名称:
- Homeobox protein PKNOX2
- Human Gene Id:
- 63876
- Human Swiss Prot No:
- Q96KN3
- Mouse Gene Id:
- 208076
- Mouse Swiss Prot No:
- Q8BG99
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human PKNOX2. AA range:341-390
- 特异性:
- PREP-2 Polyclonal Antibody detects endogenous levels of PREP-2 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- PKNOX2;PREP2;Homeobox protein PKNOX2;Homeobox protein PREP-2;PBX/knotted homeobox 2
- 实测条带:
- 55kD
- 背景:
- Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009],
- 功能:
- similarity:Belongs to the TALE/MEIS homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
- 细胞定位:
- Nucleus .
- 组织表达:
- Brain,Small intestine,
The mechanism of mulberry leaves against renal tubular interstitial fibrosis through ERK1/2 signaling pathway was predicted by network pharmacology and validated in human tubular epithelial cells. PHYTOTHERAPY RESEARCH 2019 Jun 17 WB Human 1:400 HK-2 cell
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of various cells using PREP-2 Polyclonal Antibody
- Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
- Western blot analysis of lysates from HepG2 cells, using PKNOX2 Antibody. The lane on the right is blocked with the synthesized peptide.