PLA1A Polyclonal Antibody
- 货号：YT3783
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Rat;Mouse;
- 简介：
- >>Glycerophospholipid metabolism;>>Ras signaling pathway
- 蛋白名称：
- Phospholipase A1 member A
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human PLA1A. AA range:381-430
- 特异性：
- PLA1A Polyclonal Antibody detects endogenous levels of PLA1A protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- PLA1A;NMD;PSPLA1;Phospholipase A1 member A;Phosphatidylserine-specific phospholipase A1;PS-PLA1
- 背景：
- The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011],
- 功能：
- function:Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,tissue specificity:Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.,
- 组织表达：
- Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.
- Western Blot analysis of 3T3 cells using PLA1A Polyclonal Antibody
- Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is blocked with the synthesized peptide.
