p44S10 Polyclonal Antibody
- 货号:YT3517
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse;Rat
- 简介:
- >>Proteasome;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Spinocerebellar ataxia;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Epstein-Barr virus infection
- 蛋白名称:
- 26S proteasome non-ATPase regulatory subunit 6
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human PSMD6. AA range:201-250
- 特异性:
- p44S10 Polyclonal Antibody detects endogenous levels of p44S10 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- PSMD6;KIAA0107;PFAAP4;26S proteasome non-ATPase regulatory subunit 6;26S proteasome regulatory subunit RPN7;26S proteasome regulatory subunit S10;Breast cancer-associated protein SGA-113M;Phosphonoformate immuno-associated protein 4;
- 背景:
- This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012],
- 功能:
- function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Belongs to the proteasome subunit S10 family.,similarity:Contains 1 PCI domain.,subunit:Component of the PA700 complex.,
- 细胞定位:
- proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle,proteasome accessory complex,extracellular exosome,
- 组织表达:
- Bone marrow,Lymph,Mammary cancer,Ovary,Placenta,Testis,
- Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).