• 靶点：
• P2RY8

• 简介：
• >>Neuroactive ligand-receptor interaction

• 基因名称：
• P2RY8

• 蛋白名称：
• P2Y purinoceptor 8

• Human Gene Id：
• 286530

• Human Swiss Prot No：
• Q86VZ1

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human P2RY8. AA range:192-241

• 特异性：
• P2RY8 Polyclonal Antibody detects endogenous levels of P2RY8 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• P2RY8;P2Y purinoceptor 8;P2Y8

• 实测条带：
• 41kD

• 背景：
• purinergic receptor P2Y8(P2RY8) Homo sapiens The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008],

• 功能：
• function:Probable receptor for purines coupled to G-proteins.,induction:Down-regulated during granulocytic regulation.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.,

• 细胞定位：
• Cell membrane; Multi-pass membrane protein.

• 组织表达：
• Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.

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