• 靶点：
• NTR1

• 简介：
• >>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction

• 基因名称：
• NTSR1

• 蛋白名称：
• Neurotensin receptor type 1

• Human Gene Id：
• 4923

• Human Swiss Prot No：
• P30989

• Mouse Gene Id：
• 18216

• Mouse Swiss Prot No：
• O88319

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human NTR1. AA range:181-230

• 特异性：
• NTR1 Polyclonal Antibody detects endogenous levels of NTR1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• NTSR1;NTRR;Neurotensin receptor type 1;NT-R-1;NTR1;High-affinity levocabastine-insensitive neurotensin receptor;NTRH

• 实测条带：
• 46kD

• 背景：
• Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. [provided by RefSeq, Jul 2008],

• 功能：
• function:Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.,online information:Neurotensin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein . Membrane raft . Palmitoylation is required for localization at CAV1-enriched membrane rafts. .

• 组织表达：
• Expressed in prostate (at protein level). Detected in colon and peripheral blood mononuclear cells. Detected at very low levels in brain.

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