• 靶点：
• Myp

• 基因名称：
• NOL3

• 蛋白名称：
• Nucleolar protein 3

• Human Gene Id：
• 8996

• Human Swiss Prot No：
• O60936-2

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human ARC. AA range:159-208

• 特异性：
• Myp Polyclonal Antibody detects endogenous levels of Myp protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Myp;NOL3;Nop30;Nucleolar protein 3;apoptosis repressor ARC;apoptosis repressor with CARD;apoptosis repressor with caspase recruitment domain (CARD);muscle-enriched cytoplasmic protein;nucleolar protein of 30 kDa

• 实测条带：
• 28kD

• 背景：
• NOL3 encodes an anti-apoptotic protein nucleolar protein 3 that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for NOL3.

• 细胞定位：
• [Isoform 1]: Nucleus, nucleolus . The SR-rich C-terminus mediates nuclear localization. .; [Isoform 3]: Cytoplasm .; [Isoform 2]: Cytoplasm . Mitochondrion . Sarcoplasmic reticulum . Membrane ; Lipid-anchor . Phosphorylation at Thr-149 results in translocation to mitochondria. Colocalized with mitochondria in response to oxidative stress. .

• 组织表达：
• Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas.

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