• 靶点：
• Maspin

• 简介：
• >>p53 signaling pathway;>>MicroRNAs in cancer

• 基因名称：
• SERPINB5

• 蛋白名称：
• Serpin B5

• Human Gene Id：
• 5268

• Human Swiss Prot No：
• P36952

• Mouse Gene Id：
• 20724

• Mouse Swiss Prot No：
• P70124

• Rat Gene Id：
• 116589

• Rat Swiss Prot No：
• P70564

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140

• 特异性：
• Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SERPINB5;PI5;Serpin B5;Maspin;Peptidase inhibitor 5;PI-5

• 实测条带：
• 40kD

• 背景：
• function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,

• 功能：
• function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,

• 细胞定位：
• Secreted, extracellular space.

• 组织表达：
• Normal mammary epithelial cells.

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