LRRK1 Polyclonal Antibody
- 货号:YT2594
- 应用:IHC;IF;ELISA
- 种属:Human;Mouse
- 蛋白名称:
- Leucine-rich repeat serine/threonine-protein kinase 1
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human LRRK1. AA range:361-410
- 特异性:
- LRRK1 Polyclonal Antibody detects endogenous levels of LRRK1 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- LRRK1;KIAA1790;Leucine-rich repeat serine/threonine-protein kinase 1
- 背景:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,
- 功能:
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium or manganese.,enzyme regulation:Binding of GTP stimulates kinase activity.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ROCO subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 Roc domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,similarity:Contains 4 ANK repeats.,
- 组织表达:
- Brain,Cervix,Lung,Macrophage,Pancreas,Skin,Spleen,
- Immunofluorescence analysis of HeLa cells, using LRRK1 Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LRRK1 Antibody. The picture on the right is blocked with the synthesized peptide.