• 靶点：
• LRP3

• 基因名称：
• LRP3

• 蛋白名称：
• Low-density lipoprotein receptor-related protein 3

• Human Gene Id：
• 4037

• Human Swiss Prot No：
• O75074

• Rat Gene Id：
• 89787

• Rat Swiss Prot No：
• O88204

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human LRP3. AA range:17-66

• 特异性：
• LRP3 Polyclonal Antibody detects endogenous levels of LRP3 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• LRP3;Low-density lipoprotein receptor-related protein 3;LRP-3;105 kDa low-density lipoprotein receptor-related protein;hLRp105

• 实测条带：
• 80kD

• 背景：
• function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,

• 功能：
• function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise role is however unclear, since it does not bind to very low density lipoprotein (VLDL) or to LRPAP1 in vitro.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 4 LDL-receptor class A domains.,subunit:Binds GGA1 and GGA2.,tissue specificity:Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.,

• 细胞定位：
• Membrane ; Single-pass type I membrane protein . Membrane, coated pit .

• 组织表达：
• Widely expressed. Highly expressed in skeletal muscle and ovary. Expressed at intermediate level in heart, brain, liver, pancreas, prostate and small intestine. Weakly expressed in testis, colon and leukocyte.

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