LASS4 Polyclonal Antibody
- 货号:YT2536
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Mouse
- 简介:
- >>Sphingolipid metabolism;>>Metabolic pathways;>>Sphingolipid signaling pathway
- 蛋白名称:
- Ceramide synthase 4
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90
- 特异性:
- LASS4 Polyclonal Antibody detects endogenous levels of LASS4 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CERS4;LASS4;Ceramide synthase 4;CerS4;LAG1 longevity assurance homolog 4
- 背景:
- function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,
- 功能:
- function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,
- 细胞定位:
- Endoplasmic reticulum membrane ; Multi-pass membrane protein .
- 组织表达:
- Cerebellum,Embryo,Lung,
- Western Blot analysis of various cells using LASS4 Polyclonal Antibody
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LASS4 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from HUVEC, COLO, and Jurkat cells, using LASS4 Antibody. The lane on the right is blocked with the synthesized peptide.