LASS4 Polyclonal Antibody

    • 货号:YT2536
    • 应用:WB;IHC;IF;ELISA
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • LASS4
      • 简介:
      • >>Sphingolipid metabolism;>>Metabolic pathways;>>Sphingolipid signaling pathway
      • 基因名称:
      • CERS4
      • 蛋白名称:
      • Ceramide synthase 4
      • Human Swiss Prot No:
      • Q9HA82
      • Mouse Swiss Prot No:
      • Q9D6J1
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human LASS4. AA range:41-90
      • 特异性:
      • LASS4 Polyclonal Antibody detects endogenous levels of LASS4 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CERS4;LASS4;Ceramide synthase 4;CerS4;LAG1 longevity assurance homolog 4
      • 实测条带:
      • 46kD
      • 背景:
      • function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,
      • 功能:
      • function:May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 TLC (TRAM/LAG1/CLN8) domain.,
      • 细胞定位:
      • Endoplasmic reticulum membrane ; Multi-pass membrane protein .
      • 组织表达:
      • Cerebellum,Embryo,Lung,
      • 产品图片
      • Western Blot analysis of various cells using LASS4 Polyclonal Antibody
      • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using LASS4 Antibody. The picture on the right is blocked with the synthesized peptide.
      • Western blot analysis of lysates from HUVEC, COLO, and Jurkat cells, using LASS4 Antibody. The lane on the right is blocked with the synthesized peptide.