- 靶点:
- IgA
- 基因名称:
- IGHA1/IGHA2
- 蛋白名称:
- Ig alpha-1 chain C region/Ig alpha-2 chain C region
- Human Gene Id:
- 3493/3494
- Human Swiss Prot No:
- P01876/P01877
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human IgA. AA range:227-276
- 特异性:
- IgA Polyclonal Antibody detects endogenous levels of IgA protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- IGHA1;Ig alpha-1 chain C region;IGHA2;Ig alpha-2 chain C region
- 实测条带:
- 38kD
- 背景:
- disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.,function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.,PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Monomeric or polymeric.,
- 功能:
- disease:A chromosomal aberration involving IGHA1 is found in multiple myeloma (MM) cell lines. Translocation t(1;14)(q21;q32) that forms a FCRL4-IGHA1 fusion protein.,function:Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.,PTM:3-Hydroxykynurenine, an oxidized tryptophan metabolite that is common in biological fluids, reacts with alpha-1-microglobulin to form heterogeneous polycyclic chromophores including hydroxanthommatin. The chromophore reacts with accessible cysteines forming non-reducible thioether cross-links with Ig alpha-1 chain C region Cys-352.,similarity:Contains 3 Ig-like (immunoglobulin-like) domains.,subunit:Monomeric or polymeric.,
- 细胞定位:
- Secreted . Cell membrane .
- 组织表达:
- Bile,Colon,Mammary gland,Stomach mucosa,
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of various cells using IgA Polyclonal Antibody
- Immunohistochemistry analysis of IgA antibody in paraffin-embedded human lung carcinoma tissue.
- Western blot analysis of lysate from HeLa cells, using IgA antibody.