ICAM-2 Polyclonal Antibody
- 货号：YT2270
- 应用：WB;ELISA
- 种属：Human;Mouse
- 简介：
- >>Cell adhesion molecules;>>Natural killer cell mediated cytotoxicity
- 蛋白名称：
- Intercellular adhesion molecule 2
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human ICAM2. AA range:151-200
- 特异性：
- ICAM-2 Polyclonal Antibody detects endogenous levels of ICAM-2 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- ICAM2;Intercellular adhesion molecule 2;ICAM-2;CD antigen CD102
- 背景：
- The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
- 功能：
- function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.,online information:ICAM-2,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,
- 细胞定位：
- Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Co-localizes with RDX, EZR and MSN in microvilli. .
- 组织表达：
- Aorta endothelial cell,Blood,Brain,Endothelial cell,Plasma,Spleen,
- Western Blot analysis of 3T3 cells using ICAM-2 Polyclonal Antibody
- Western blot analysis of the lysates from HT-29 cells using ICAM2 antibody.
