• 靶点：
• Granzyme K

• 基因名称：
• GZMK

• 蛋白名称：
• Granzyme K

• Human Gene Id：
• 3003

• Human Swiss Prot No：
• P49863

• Mouse Gene Id：
• 14945

• Mouse Swiss Prot No：
• O35205

• Rat Gene Id：
• 29165

• Rat Swiss Prot No：
• P49864

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110

• 特异性：
• Granzyme K Polyclonal Antibody detects endogenous levels of Granzyme K protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• GZMK;TRYP2;Granzyme K;Fragmentin-3;Granzyme-3;NK-tryptase-2;NK-Tryp-2

• 实测条带：
• 33kD

• 背景：
• This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008],

• 功能：
• similarity:Belongs to the peptidase S1 family. Granzyme subfamily.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Expressed in lung, spleen, thymus and peripheral blood leukocytes.,

• 细胞定位：
• Secreted. Cytoplasmic granule.

• 组织表达：
• Expressed in lung, spleen, thymus and peripheral blood leukocytes.

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