GPR139 Polyclonal Antibody
- 货号:YT1972
- 应用:WB;IF;ELISA
- 种属:Human;Mouse;Rat
- 蛋白名称:
- Probable G-protein coupled receptor 139
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human GPR139. AA range:181-230
- 特异性:
- GPR139 Polyclonal Antibody detects endogenous levels of GPR139 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- GPR139;GPRG1;PGR3;Probable G-protein coupled receptor 139;G(q)-coupled orphan receptor GPRg1;G-protein-coupled receptor PGR3
- 背景:
- This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
- 功能:
- function:Orphan receptor. Seems to act through a G(q/11)-mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.,
- 细胞定位:
- Cell membrane; Multi-pass membrane protein.
- 组织表达:
- Expressed almost exclusively in the brain. Detected at very low levels in the peripheral tissues.
![](/uploadfiles/PIC/yt1972-wb.jpg)
- Western Blot analysis of K562 cells using GPR139 Polyclonal Antibody
![](/uploadfiles/PIC/yt1972_pic844218522.jpg)
- Immunofluorescence analysis of LOVO cells, using GPR139 Antibody. The picture on the right is blocked with the synthesized peptide.