GPR124 Polyclonal Antibody
- 货号：YT1966
- 应用：WB;IF;ELISA
- 种属：Human;Mouse
- 蛋白名称：
- G-protein coupled receptor 124
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human GPR124. AA range:1151-1200
- 特异性：
- GPR124 Polyclonal Antibody detects endogenous levels of GPR124 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- GPR124;KIAA1531;TEM5;G-protein coupled receptor 124;Tumor endothelial marker 5
- 背景：
- caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,
- 功能：
- caution:It is uncertain whether Met-1 or Met-8 is the initiator.,domain:Binds to DLG1 through its PDZ-binding motif.,function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 5 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1.,tissue specificity:Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.,
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein . Cell projection, filopodium . Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. .
- 组织表达：
- Expressed in endothelial cells (at protein level) (PubMed:15021905, PubMed:16982628). Abundantly expressed in heart, placenta, ovary, small intestine, and colon (PubMed:15021905).
- Immunofluorescence analysis of HeLa cells, using GPR124 Antibody. The picture on the right is blocked with the synthesized peptide.
